New DNA-encoded chemical library technology to aid drug discovery and development
(Science and Technology Daily) Although researchers have made significant progress in the development of molecular therapies in recent years, the number of newly discovered active substances remains insufficient. Now, the DNA-encoded chemical library (DEL) technology, jointly developed by Harvard University in the US and ETH Zurich in Switzerland, offers a new solution. The technology can automate the synthesis and testing of billions of compounds in a matter of weeks, and can also be used to produce larger drug molecules that will act on targets that are difficult to reach with traditional small molecules.
Sep 25,2024
Colorful Nucleotide Derivatives in Cells
ATP (adenosine triphosphate) is one of the products of biological oxidation and is central to the release, storage and utilization of energy in living organisms.ATP contains two high-energy phosphoric acid bonds and emits at least 30kJ/mol of free energy on hydrolysis.
Sep 25,2024
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